Even if there’s an underlying order to all of existence, it seems readily evident that we can be placed in such a depth of darkness that this underlying order becomes inconsequential. (If you don’t want to comb through historic atrocities, you could always watch “Bone Tomahawk.”)
However, what seems to consistently lift the spirit is when someone honestly assesses their present situation, and does what they can to improve their lot. The idea of a worthy challenge that one can conquer (even if it it’s small) apparently will generate solace in the darkest of circumstances. This seems to be supported by psychology, as well as anecdotes of prisoners and documented horrors.
This simplifies things for me; it shifts my focus away from proving some grand truth, and to the immediate question of “What do I do now, with what I’ve got in front of me?”